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Coronavirus Updates

Regeneron Pharmaceuticals launched clinical trials last week of an antibody cocktail intended to both prevent and treat COVID-19.

The antibody cocktail — called REGN-COV2 — is composed of antibodies, akin to those produced naturally in the body, but selected for maximum potency and strength. When injected, the antibodies protect the body from COVID-19 infection. Unlike vaccines, which are only used preventatively, they can also treat an existing infection. The company created REGN-COV2 using a similar approach to how it created REGN-EB3, a triple antibody treatment for Ebola, which the U.S. Food and Drug Administration (FDA) is currently reviewing.

According to the press release, the clinical trials will consist of four separate study populations: two for treatment and two for prevention.

The drug will be given to hospitalized COVID-19 patients and non-hospitalized symptomatic COVID-19 patients to assess its safety and efficacy as a treatment.

To test how it works as a preventative measure, the drug will also be given to uninfected people in groups that are at high-risk of exposure (such as healthcare workers or first responders) and uninfected people with close exposure to a COVID-19 patient (such as the patient's housemate).

The trials will be conducted at multiple sites.

Read more about the trials.

Watch our latest HealthDay Now as we dive into the latest details on multisystem inflammatory syndrome in children (MIS-C).

Mabel Jong from our liveblog team speaks with Dr. Mary Beth Son, Program Director of Boston Children's Hospital's Rheumatology Program, and Brian Padla, father of James Padla, who has MIS-C.

Watch the in-depth discussion above, and see our past HealthDay Nows and other videos on our YouTube channel.


HD Live! Videos

Watch our latest HD Live! as we take a look at the global COVID-19 vaccination rollout and how the United States rollout compares.

Mabel Jong from our liveblog team speaks with Dr. Ran Balicer of Clalit Health Services and Dr. Arnold Monto of University of Michigan School of Public Health.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

UPDATE 1/26/21: Since our HD Live! interview with CEO Andrei Doroshin, the Philadelphia Health Department has severed its ties with the organization. The nonprofit has changed its status to a for-profit entity.

Watch our latest HD Live! as we take a look at Philly Fighting Covid, a nonprofit organization run by graduate students from Drexel University that aims to help with mass COVID-19 vaccination in Philadelphia.

Mabel Jong from our liveblog team speaks with Andrei Doroshin, founder of Philly Fighting Covid.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a deep dive into the vaccine rollout across the country.

Mabel Jong from our liveblog team speaks with Dr. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota and a member of the Biden COVID-19 Advisory Board.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a deep dive into the latest information on the COVID-19 vaccines, including the rollout process, potential side effects, supply and distribution.

Mabel Jong from our liveblog team speaks with Dr. Paul Offit, Director of the Vaccine Education Center and an attending physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia and one of the physicians on the FDA Vaccines and Related Biological Products Advisory Committee.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a look back and a look ahead at COVID-19 and its impact on the United States and its healthcare workers.

Mabel Jong from our liveblog team speaks with Dr. David Shulkin, former Secretary of Veterans Affairs, ex-CEO of Beth Israel Medical Center in New York and an accomplished healthcare executive, and Dr. Joel Zivot, anesthesiologist and clinician at Emory University Hospital ICU.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! with Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID).

Mabel Jong from our liveblog team speaks with Dr. Anthony Fauci about the latest on COVID-19, including the vaccines, the infection rates and the future.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! is a conference wrap-up of the American Heart Association Scientific Sessions 2020.

Mabel Jong from our liveblog team speaks with Dr. Donald Lloyd-Jones, American Heart Association President-Elect, for a summary of the highlights of the AHA Scientific Sessions 2020.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is on how healthcare in America could be impacted by a Trump or Biden victory.

Mabel Jong from our liveblog team speaks with Marianne Udow-Phillips, director of the Center for Health and Research Transformation at the University of Michigan, and Brian Blase, who served as a healthcare adviser to President Trump from 2017-2019 and is now president and CEO of Blase Policy Strategies.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.