Back to top
Live:
Coronavirus Updates

Each week, HealthDay's Physician's Briefing division rounds up the most important COVID-19 developments in the medical field. See this week's edition below for April 6th-April 10th.

FDA Approves New Way to Decontaminate N95 Face Masks

FRIDAY, April 10, 2020 (HealthDay News) -- The second emergency use authorization to decontaminate N95 face masks and equivalents for reuse by hospital health care workers has been issued by the U.S. Food and Drug Administration.

Read Full Article

Temperature, UV Radiation Not Linked to Incidence of COVID-19

FRIDAY, April 10, 2020 (HealthDay News) -- Ambient temperature and ultraviolet (UV) radiation are not associated with the cumulative incidence rate or basic reproduction number (R0) of coronavirus disease 2019 (COVID-19), according to a research letter published online April 8 in the European Respiratory Journal.

Read Full Article

Neurologic Effects Seen in a Third of Hospitalized COVID-19 Patients

FRIDAY, April 10, 2020 (HealthDay News) -- Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.

Read Full Article

Contact Tracing ID'd Large Multifamily COVID-19 Cluster in Chicago

FRIDAY, April 10, 2020 (HealthDay News) -- One index patient with COVID-19 and only mild symptoms attended two family gatherings and likely triggered a chain of transmission that included 15 other confirmed and probable cases with three deaths, according to research published in the April 8 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

Doctors Report on Four COVID-19 Infections in Newborns in China

FRIDAY, April 10, 2020 (HealthDay News) -- Compared with adults, symptoms of COVID-19 in newborn babies are milder and outcomes are less severe, according to a research letter published online April 8 in the European Respiratory Journal.

Read Full Article

Current Models for COVID-19 Diagnosis, Prognosis Unreliable

FRIDAY, April 10, 2020 (HealthDay News) -- Novel coronavirus-related models that are published in the literature are poorly reported and at high risk for bias, raising concern that their predictions could be unreliable when applied in daily practice, according to a review published online April 7 in The BMJ.

Read Full Article

Face Masks Offer Slight Protective Effect From Flu-Like Illness

FRIDAY, April 10, 2020 (HealthDay News) -- Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact, according to a review that has not yet been peer reviewed and was posted online April 6 at medRxiv.org.

Read Full Article

Anxiety Up for Nonmedical Health Care Workers Versus Those on Front Lines

FRIDAY, April 10, 2020 (HealthDay News) -- Non-medically trained health care workers caring for patients with coronavirus disease 2019 have an increased prevalence of anxiety compared with medically trained health care workers, according to a research letter published online April 6 in the Annals of Internal Medicine.

Read Full Article

Clinical Trial Underway to Test Nitric Oxide in COVID-19 Patients

THURSDAY, April 9, 2020 (HealthDay News) -- Doctors at the University of Alabama at Birmingham are enrolling patients in an international clinical trial to find out if inhaled nitric oxide benefits those with novel coronavirus who have severely damaged lungs.

Read Full Article

COVID-19 Came to New York City From Europe, Not Asia

THURSDAY, April 9, 2020 (HealthDay News) -- The novel coronavirus has been circulating in New York City for longer than previously believed and most cases can be traced back to Europe, new research reveals.

Read Full Article

NIH Launches Clinical Trial of Hydroxychloroquine for COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A clinical trial to assess the antimalarial drug hydroxychloroquine as a treatment for adults with the novel coronavirus is now underway, the U.S. National Institutes of Health said Thursday.

Read Full Article

FDA Warns of False Claims That Chlorine Dioxide Can Treat COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A warning letter has been sent to a company marketing fraudulent and dangerous chlorine dioxide products for the prevention and treatment of the novel coronavirus, the U.S. Food and Drug Administration says.

Read Full Article

Another COVID-19 Vaccine Trial Begins in the United States

THURSDAY, April 9, 2020 (HealthDay News) -- Another clinical trial of an experimental vaccine for the novel coronavirus 2019 has been launched by U.S. researchers.

Read Full Article

Older Adults, Men, Preexisting Conditions Tied to COVID-19 Death

THURSDAY, April 9, 2020 (HealthDay News) -- Researchers have identified the most common clinical characteristics among 109 patients out of 1,017 with confirmed novel coronavirus pneumonia who died of COVID-19-related pneumonia in Wuhan, China; their findings were published online April 7 in the Annals of the American Thoracic Society.

Read Full Article

Convalescent Plasma Treatment Promising in Severe COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- One dose of convalescent plasma therapy is well tolerated and can potentially improve clinical symptoms in severe cases with coronavirus disease 2019, according to a study published online April 6 in the Proceedings of the National Academy of Sciences.

Read Full Article

ATS Provides Interim Guidance for Management of COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- In a guidance document issued by the American Thoracic Society, interim recommendations are presented for management of coronavirus disease 2019.

Read Full Article

HHS Report Looks at Hospital Experiences With COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A report issued by the U.S. Department of Health and Human Services Office of Inspector General provides a national snapshot of hospital experiences in response to the coronavirus disease 2019.

Read Full Article

CDC Removes Prescribing Guidelines for Antimalarial Drugs

WEDNESDAY, April 8, 2020 (HealthDay News) -- Guidelines for doctors on how to prescribe two antimalarial drugs that some believe may treat the novel coronavirus are no longer available on the U.S. Centers for Disease Control and Prevention website.

Read Full Article

COVID-19 Killing Two Times More Men Than Women in NYC

WEDNESDAY, April 8, 2020 (HealthDay News) -- The novel coronavirus death rate in New York City is two times higher among men than among women, and men also have higher rates of infection and hospitalization, new data show.

Read Full Article

Children With COVID-19 Do Not Always Have Cough, Fever

WEDNESDAY, April 8, 2020 (HealthDay News) -- Children with coronavirus disease 2019 have symptoms of fever, cough, or shortness of breath less often than adults with the disease, according to research published in the April 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

Surgical, Cotton Masks Not Effective for Filtering SARS-CoV-2

WEDNESDAY, April 8, 2020 (HealthDay News) -- For patients infected with severe acute respiratory syndrome coronavirus 2, neither surgical nor cotton masks effectively filter SARS-CoV-2 during coughs, according to a research letter published online April 6 in the Annals of Internal Medicine.

Read Full Article

Guidelines Developed for COVID-19 Patients in ICU

WEDNESDAY, April 8, 2020 (HealthDay News) -- In guidelines issued by the international Surviving Sepsis Campaign initiative, published in Critical Care Medicine and Intensive Care Medicine, recommendations are presented for the management of novel coronavirus disease 2019 patients in the intensive care unit.

Read Full Article

Children Have Milder Disease Course, Better COVID-19 Prognosis

WEDNESDAY, April 8, 2020 (HealthDay News) -- Children diagnosed with COVID-19 have a milder disease course and better prognoses than adults, according to a review published online March 23 in Acta Paediatrica.

Read Full Article

Side Effects Seen With Use of Chloroquine Against COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- The use of the antimalarial drug chloroquine to treat COVID-19 patients has been halted at several Swedish hospitals due to reported side effects such as cramps and loss of peripheral vision. Sahlgrenska University Hospital is one of those facilities. It stopped the use of chloroquine in the treatment of COVID-19 about two weeks ago.

Read Full Article

Serious Concerns Associated With COVID-19 Pandemic Reported

TUESDAY, April 7, 2020 (HealthDay News) -- Serious concerns are associated with coronavirus disease 2019, and many individuals are preparing by washing hands and self-isolating, according to a research letter published online April 7 in JAMA Internal Medicine.

Read Full Article

Compliance Higher if Stay-at-Home Extensions Are Shorter Than Thought

TUESDAY, April 7, 2020 (HealthDay News) -- When hypothetical stay-at-home orders in response to COVID-19 are extended longer than expected, people become less willing to increase self-isolation efforts, according to a working paper released by the National Bureau of Economic Research.

Read Full Article

Most COVID-19 Fatalities Are Men Over 50 With Chronic Disease

TUESDAY, April 7, 2020 (HealthDay News) -- Most fatal cases of coronavirus disease 2019 occur in men aged older than 50 years with noncommunicable chronic diseases, according to a study published online April 3 in the American Journal of Respiratory and Critical Care Medicine.

Read Full Article

Recommendations Issued for GI Procedures During COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- In a document issued by the American Gastroenterological Association, published online April 1 in Gastroenterology, recommendations are presented for gastrointestinal procedures during the coronavirus disease 2019 pandemic.

Read Full Article

School Closures Could Further Complicate COVID-19 Effort

TUESDAY, April 7, 2020 (HealthDay News) -- Potential contagion prevention from school closures needs to be weighed against the potential loss of health care workers due to child care obligations during the coronavirus disease 2019 pandemic, according to a study published online April 3 in The Lancet Public Health.

Read Full Article

No Treatment Change Needed for Peds IBD During COVID-19 Pandemic

TUESDAY, April 7, 2020 (HealthDay News) -- Preliminary data regarding outcomes for pediatric patients with inflammatory bowel disease during the coronavirus disease 2019 outbreak are reassuring, according to research published online March 31 in the Journal of Pediatric Gastroenterology and Nutrition.

Read Full Article

Radiotherapy for Prostate Cancer Adjusted During COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- In a special article published online April 1 in Advances in Radiation Oncology, a framework is laid out for the management of radiotherapy for prostate cancer patients during the coronavirus disease 2019 pandemic.

Read Full Article

FDA Authorizes Use of Chinese-Approved Masks in United States

MONDAY, April 6, 2020 (HealthDay News) -- Emergency use authorization of protective masks that do not meet American standards has been announced by the U.S. Food and Drug Administration.

Read Full Article

Majority of Physicians Report Serious Concerns About COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- According to a national survey conducted by Harvard Medical School, the RAND Corporation, and Doximity, practicing physicians currently report substantial concerns about supplies, the government response, and availability of testing amid the COVID-19 pandemic.

Read Full Article

Social Distancing Minimizes COVID-19 Spread in Assisted Living

MONDAY, April 6, 2020 (HealthDay News) -- Early implementation of social distancing and preventive measures after identification of coronavirus disease 2019 can minimize virus spread in senior independent and assisted living communities, according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

Sentinel Surveillance Can Help Monitor Epidemiology of COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Rapid sentinel surveillance can help monitor the epidemiology of coronavirus disease 2019, according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

Hydroxychloroquine Can Shorten Time to Recovery in COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Hydroxychloroquine can shorten time to clinical recovery and promote pneumonia absorption among patients with coronavirus disease 2019, according to a study that has not yet been peer reviewed and was posted online March 31 at medRxiv.org.

Read Full Article

Extracorporeal Membrane Oxygenation Might Aid in Severe COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Extracorporeal membrane oxygenation support might improve clinical outcomes in severe cases of coronavirus disease 2019 that cannot be adequately managed with mechanical ventilation alone, according to research published online March 30 in the ASAIO Journal.

Read Full Article

Comorbidity, Age, Time to Treatment Linked to COVID-19 Progression

MONDAY, April 6, 2020 (HealthDay News) -- Factors associated with coronavirus disease 2019 progression include comorbidity, age, and time from illness onset to antiviral treatment, according to a study published online March 27 in the Journal of Internal Medicine.

Read Full Article

Each week, HealthDay's Physician's Briefing division rounds up the most important COVID-19 developments in the medical field. See this week's edition below for July 6-July 10.

Gilead Presents Additional Data on Efficacy of Remdesivir for COVID-19

FRIDAY, July 10, 2020 (HealthDay News) -- There is more good news on the effectiveness of the antiviral drug remdesivir against COVID-19, according to new clinical trial results from the drug's maker.

Read Full Article

Risk for COVID-19 Increased for Adults Taking PPIs

FRIDAY, July 10, 2020 (HealthDay News) -- Adults taking proton pump inhibitors have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship, according to a study published online July 7 in preprint format in the American Journal of Gastroenterology.

Read Full Article

WHO to Lead Investigation of COVID-19 Pandemic Origins

FRIDAY, July 10, 2020 (HealthDay News) -- The World Health Organization will lead an international investigation into the origins of the COVID-19 pandemic in China.

Read Full Article

Emphasizing Severity of COVID-19 Important for Teen Behaviors

FRIDAY, July 10, 2020 (HealthDay News) -- For adolescents, understanding the severity of COVID-19 and valuing social responsibility are associated with acting in socially responsible ways, including more social distancing and disinfecting, according to a study published online June 29 in JAMA Pediatrics.

Read Full Article

Children Seem Not to Be Driving SARS-COV-2 Transmission

FRIDAY, July 10, 2020 (HealthDay News) -- Children are mainly infected with severe acute respiratory syndrome coronavirus 2 in familial clusters, suggesting that transmission in schools is likely to be less than expected and that school closures are not necessary, according to a study and accompanying editorial published online July 10 in Pediatrics.

Read Full Article

COVID-19 Explored in Kidney Recipients, Hemodialysis Patients

FRIDAY, July 10, 2020 (HealthDay News) -- Many outpatient kidney transplant recipients with COVID-19 have symptomatic resolution without requiring hospitalization, and hospitalized COVID-19 patients on hemodialysis have worse outcomes than those without kidney failure, according to two studies recently published in the Clinical Journal of the American Society of Nephrology.

Read Full Article

Incidence of Takotsubo Cardiomyopathy Up During COVID-19

FRIDAY, July 10, 2020 (HealthDay News) -- The incidence of Takotsubo cardiomyopathy has increased during the COVID-19 pandemic, according to a study published online July 9 in JAMA Network Open.

Read Full Article

Sick Days Up for Some Essential Workers During COVID-19

THURSDAY, July 9, 2020 (HealthDay News) -- Increases in health-related workplace absenteeism were seen in April 2020 in personal care and service, health care support, and production occupations, according to research published in the July 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

COVID-19 Pandemic Exacerbates Mental Health Issues

THURSDAY, July 9, 2020 (HealthDay News) -- Just as the physical symptoms of COVID-19 vary among the population, mental health is enduring a variety of effects from the virus as well, according to Don Mordecai, M.D., national mental health and wellness lead at Kaiser Permanente, who recently spoke with HD Live! about the effects of the pandemic on mental health.

Read Full Article

Spectrum of Neurological Disorders Linked to SARS-CoV-2

THURSDAY, July 9, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 infection is associated with a spectrum of neurological disorders, according to a study published online July 8 in Brain.

Read Full Article

CDC Updates Info on COVID-19 Cases at Meat, Poultry Processing Facilities

THURSDAY, July 9, 2020 (HealthDay News) -- COVID-19 was confirmed in 16,233 workers in 239 meat and poultry processing facilities in 23 states through May 31, 2020, according to research published in the July 7 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

February to March 2020 Saw Surge in Hydroxychloroquine Rx

WEDNESDAY, July 8, 2020 (HealthDay News) -- From February to March 2020, there was a considerable increase in the number of patients receiving outpatient prescriptions for hydroxychloroquine, chloroquine, and azithromycin, according to a research letter published online July 6 in JAMA Internal Medicine.

Read Full Article

Multisystem Inflammatory Syndrome in Children Profiled

WEDNESDAY, July 8, 2020 (HealthDay News) -- Multisystem inflammatory syndrome in children, which coincided with COVID-19, is described in children and adolescents in the United States and New York state in two reports published online June 29 in the New England Journal of Medicine.

Read Full Article

Rising Number of People Report Anxiety, Depression During COVID-19

WEDNESDAY, July 8, 2020 (HealthDay News) -- New evidence shows that depression and anxiety are increasing as a result of the COVID-19 pandemic, according to the results of a survey released by Mental Health America.

Read Full Article

COVID-19 Antibody Cocktail Begins Late-Stage Human Trials

TUESDAY, July 7, 2020 (HealthDay News) -- Late-stage human trials to assess whether a double antibody cocktail can prevent and treat COVID-19 infection have started, biotechnology company Regeneron said Monday.

Read Full Article

Company Gets $1.6 Billion From U.S. Government for COVID-19 Vaccine

TUESDAY, July 7, 2020 (HealthDay News) -- Vaccine maker Novavax will receive $1.6 billion from the U.S. government to provide 100 million doses of a COVID-19 vaccine by early 2021, the Maryland-based company said Monday.

Read Full Article

Acute Ischemic Stroke Risk Higher With COVID-19 Than Influenza

TUESDAY, July 7, 2020 (HealthDay News) -- Patients with COVID-19 appear to have a heightened risk for acute ischemic stroke compared with patients with influenza, according to a study published online July 2 in JAMA Neurology.

Read Full Article

Social Distancing Effective for Mitigating COVID-19 Spread

TUESDAY, July 7, 2020 (HealthDay News) -- Social distancing is one of the main measures to combat COVID-19 spread, according to a study published online July 1 in The Lancet Infectious Diseases.

Read Full Article

Chilblains in Recent Case Series Not Tied to COVID-19 Infection

TUESDAY, July 7, 2020 (HealthDay News) -- In a case series of 31 patients, published online June 25 in JAMA Dermatology, chilblains did not appear to be directly associated with COVID-19.

Read Full Article

Major Medical Groups Urge Americans to Wear Face Masks

MONDAY, July 6, 2020 (HealthDay News) -- Three major medical groups are urging Americans to wear face masks, wash their hands, and practice social distancing as COVID-19 cases continue to surge in the United States.

Read Full Article

Fight Against COVID-19 Threatens Progress Against Other Diseases

MONDAY, July 6, 2020 (HealthDay News) -- Decades of progress against HIV, tuberculosis, malaria, and other diseases worldwide are threatened by the diversion of resources on the COVID-19 pandemic, the International AIDS Society says in a report to be published this week.

Read Full Article

FDA Warns About Hand Sanitizers With Methanol

MONDAY, July 6, 2020 (HealthDay News) -- A warning about hand sanitizer products that contain methanol (wood alcohol), a substance often used to create fuel and antifreeze, has been issued by the U.S. Food and Drug Administration.

Read Full Article

Scientists Say New Coronavirus Can Linger in Indoor Air

MONDAY, July 6, 2020 (HealthDay News) -- The new coronavirus can linger in indoor air and infect people, 239 scientists in 32 countries say in an open letter to the World Health Organization that challenges the WHO's position on how the virus is spread.

Read Full Article

Endotheliopathy ID'd in COVID-19, Tied to Higher Mortality Risk

MONDAY, July 6, 2020 (HealthDay News) -- Endotheliopathy is present in COVID-19 and is associated with critical illness and death, according to a study published online June 30 in The Lancet Haematology.

Read Full Article

Outcomes Similar for COVID-19 in Patients With, Without HIV

MONDAY, July 6, 2020 (HealthDay News) -- Persons with HIV hospitalized with COVID-19 have similar outcomes to demographically matched patients without HIV, according to a study published online June 28 in Clinical Infectious Diseases.

Read Full Article

Most Using Online COVID-19 Tool Report Mild, Moderate Symptoms

MONDAY, July 6, 2020 (HealthDay News) -- The majority of individuals using an online COVID-19 self-assessment tool report mild or moderate symptoms possibly associated with COVID-19, according to research published online June 15 in the Journal of General Internal Medicine.

Read Full Article

HD Live! Videos

Our latest HD Live! discussion is on how countries have contained COVID-19 and whether the United States can do the same with universal masking and certain other health strategies.

Mabel Jong from our liveblog team speaks with Dr. Robert Brook, a professor of medicine at UCLA and the distinguished chair in the health care services program at the RAND Corporation, and Dr. May Chu, a clinical professor of epidemiology with the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

They contend that much smaller exhaled droplets can travel the length of a room and cause infection when inhaled.

Scientists Say New Coronavirus Can Linger in Indoor Air

MONDAY, July 6, 2020 (HealthDay News) -- The new coronavirus can linger in indoor air and infect people, 239 scientists in 32 countries say in an open letter to the World Health Organization that challenges the WHO's position on how the virus is spread.

The WHO says the virus is spread primarily by large respiratory droplets expelled by infected people in coughs and sneezes but that those droplets fall quickly to the floor instead of remaining in the air, The New York Times reported. But the scientists' letter contends that much smaller exhaled droplets can travel the length of a room through the air and cause infection when they are inhaled. They plan to publish their letter next week in a scientific journal.

If this type of airborne transmission plays a significant role in the pandemic, there are major implications, according to The Times. Masks may be required indoors, building ventilation systems may need to minimize recirculating air, ultraviolet lights may be required to kill airborne viral particles, and health care workers may need masks that filter out even the smallest respiratory droplets as they care for COVID-19 patients.

Read the full HealthDay story.

Methanol can be toxic when absorbed through the skin and life-threatening when ingested.

FDA Warns About Hand Sanitizers With Methanol

MONDAY, July 6, 2020 (HealthDay News) -- A warning about hand sanitizer products that contain methanol (wood alcohol), a substance often used to create fuel and antifreeze, has been issued by the U.S. Food and Drug Administration.

Methanol can be toxic when absorbed through the skin and life-threatening when ingested, and it is not an acceptable active ingredient for hand sanitizer products, according to the FDA. The agency said it has seen an increase in hand sanitizer products that are labeled to contain ethanol (also known as ethyl alcohol) but that have tested positive for methanol. Methanol exposure can result in nausea, vomiting, headache, blurred vision, permanent blindness, seizures, coma, permanent damage to the nervous system, or death.

State officials have reported recent harm among adults and children who ingested hand sanitizer products contaminated with methanol, including blindness, hospitalization, and death, the FDA said. Consumers who have hand sanitizers with methanol should immediately stop using them and dispose of the bottle in a hazardous waste container, if available, or dispose of it as recommended by their local waste management and recycling center. There is a list of FDA-tested and recalled hand sanitizers on the agency's website.

Read the full HealthDay story.

In many cities, a combination of factors are fueling the problem: a shortage of key supplies, backlogs at laboratories that perform the tests, and surging infection counts as cases climb in almost 40 states.

U.S. Coronavirus Cases Near 3 Million as Hospitals in Sun Belt Fill Up With Patients

TUESDAY, July 7, 2020 (HealthDay News) -- With the number of coronavirus cases in the United States approaching 3 million on Monday, hospitals across the Sun Belt continued to be flooded with COVID-19 patients.

Arizona reached 89 percent capacity for ICU beds, as Alabama, California, Georgia, North Carolina, South Carolina and Texas also reported unprecedented numbers of hospitalizations, the Washington Post reported.

For the 28th day in a row, the country's rolling seven-day average of daily new cases obliterated previous records, though the number of deaths nationwide has remained relatively stable, the newspaper reported.

Read the full HealthDay story.

Authors say self-assessment tool could ease burden on health care system and collect useful information.

Most Using Online COVID-19 Tool Report Mild, Moderate Symptoms

MONDAY, July 6, 2020 (HealthDay News) -- The majority of individuals using an online COVID-19 self-assessment tool report mild or moderate symptoms possibly associated with COVID-19, according to research published online June 15 in the Journal of General Internal Medicine.

William M. Mehring, from the Keck School of Medicine at the University of Southern California in Los Angeles, and colleagues developed a web-based COVID-19 self-assessment tool, available in English and Spanish, and report the results of 276,560 digital self-assessments.

The researchers report that of the 5,611 users who entered optional demographic data, 61 percent were female (mean age, 39 years). In more than two-thirds of self-assessments (69.6 percent), users reported symptoms potentially attributable to COVID-19. Among the reported symptoms potentially attributable to COVID-19, the majority (80.5 percent) reported mild or moderate symptoms that could likely be managed with home self-care, while 19.5 percent reported severe symptoms for which the tool recommended immediate medical attention. Of individuals reporting mild symptoms, 7.1 percent said they had direct exposure to someone with confirmed COVID-19.

Read the full HealthDay story.

Soluble thrombomodulin concentration >3.26 ng/mL linked to lower rates of hospital discharge and survival.

Endotheliopathy ID'd in COVID-19, Tied to Higher Mortality Risk

MONDAY, July 6, 2020 (HealthDay News) -- Endotheliopathy is present in COVID-19 and is associated with critical illness and death, according to a study published online June 30 in The Lancet Haematology.

George Goshua, M.D., from the Yale School of Medicine in New Haven, Connecticut, and colleagues conducted a single-center study involving hospitalized adult patients with laboratory-confirmed COVID-19 from the medical intensive care unit (ICU) or a specialized non-ICU COVID-19 floor (48 and 20 patients, respectively); 13 asymptomatic nonhospitalized controls were recruited as a comparator group. Markers of endothelial cell and platelet activations were assessed and the levels were compared for ICU patients, non-ICU patients, and controls.

The researchers found that compared with non-ICU patients, in ICU patients, markers of endothelial cell and platelet activation were significantly elevated, including von Willebrand Factor (VWF) antigen (mean, 565 percent in ICU patients versus 278 percent in non-ICU patients) and soluble P-selectin (15.9 versus 11.2 ng/mL). In 16 of 20 non-ICU patients, VWF antigen concentrations were also elevated above the normal range. Among all patients, there was a significant association between mortality and VWF antigen and soluble thrombomodulin. Soluble thrombomodulin concentrations greater than 3.26 ng/mL were associated with lower rates of hospital discharge (88 versus 52 percent) and a lower likelihood of survival (hazard ratio, 5.9).

Read the full HealthDay story.

See what experts have to say about the toll of the COVID-19 pandemic on mental health.

Will the COVID-19 Pandemic Leave a Mental Health Crisis in Its Wake?

MONDAY, July 6, 2020 (HealthDay News) -- Stressed from home-schooling your kids? Lonely from lockdown? Worried about a sick loved one isolated in a nursing home? Worried you might lose your job?

The ongoing COVID-19 pandemic is affecting everyone's mental health in ways small and large, and experts are concerned that for many, today's anxiety will become a tidal wave of mental health problems in the years ahead.

The pandemic is adding to what already was an underrecognized mental health crisis in the United States, according to Dr. Don Mordecai, national mental health and wellness lead at Kaiser Permanente in Oakland, Calif.

Read the full HealthDay story.

In a small study, all 10 patients who had severe COVID-19 symptoms produced T-cells that worked with antibodies to try to kill the virus and stop the infection.

How Immune System Fights COVID-19 May Be Key to Vaccine Success

MONDAY, July 6, 2020 (HealthDay News) -- Even the sickest COVID-19 patients make T-cells to fight the infection, a new study finds.

This means that a COVID-19 vaccine will have to cause the body to make T-cells along with antibodies, researchers say.

The immune response to the SARS-CoV-2 virus, which causes COVID-19, was the same in American and Dutch patients in the study.

Read the full HealthDay story.