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Each week, HealthDay's Physician's Briefing division rounds up the most important COVID-19 developments in the medical field. See this week's edition below for April 6th-April 10th.

FDA Approves New Way to Decontaminate N95 Face Masks

FRIDAY, April 10, 2020 (HealthDay News) -- The second emergency use authorization to decontaminate N95 face masks and equivalents for reuse by hospital health care workers has been issued by the U.S. Food and Drug Administration.

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Temperature, UV Radiation Not Linked to Incidence of COVID-19

FRIDAY, April 10, 2020 (HealthDay News) -- Ambient temperature and ultraviolet (UV) radiation are not associated with the cumulative incidence rate or basic reproduction number (R0) of coronavirus disease 2019 (COVID-19), according to a research letter published online April 8 in the European Respiratory Journal.

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Neurologic Effects Seen in a Third of Hospitalized COVID-19 Patients

FRIDAY, April 10, 2020 (HealthDay News) -- Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.

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Contact Tracing ID'd Large Multifamily COVID-19 Cluster in Chicago

FRIDAY, April 10, 2020 (HealthDay News) -- One index patient with COVID-19 and only mild symptoms attended two family gatherings and likely triggered a chain of transmission that included 15 other confirmed and probable cases with three deaths, according to research published in the April 8 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Doctors Report on Four COVID-19 Infections in Newborns in China

FRIDAY, April 10, 2020 (HealthDay News) -- Compared with adults, symptoms of COVID-19 in newborn babies are milder and outcomes are less severe, according to a research letter published online April 8 in the European Respiratory Journal.

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Current Models for COVID-19 Diagnosis, Prognosis Unreliable

FRIDAY, April 10, 2020 (HealthDay News) -- Novel coronavirus-related models that are published in the literature are poorly reported and at high risk for bias, raising concern that their predictions could be unreliable when applied in daily practice, according to a review published online April 7 in The BMJ.

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Face Masks Offer Slight Protective Effect From Flu-Like Illness

FRIDAY, April 10, 2020 (HealthDay News) -- Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact, according to a review that has not yet been peer reviewed and was posted online April 6 at medRxiv.org.

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Anxiety Up for Nonmedical Health Care Workers Versus Those on Front Lines

FRIDAY, April 10, 2020 (HealthDay News) -- Non-medically trained health care workers caring for patients with coronavirus disease 2019 have an increased prevalence of anxiety compared with medically trained health care workers, according to a research letter published online April 6 in the Annals of Internal Medicine.

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Clinical Trial Underway to Test Nitric Oxide in COVID-19 Patients

THURSDAY, April 9, 2020 (HealthDay News) -- Doctors at the University of Alabama at Birmingham are enrolling patients in an international clinical trial to find out if inhaled nitric oxide benefits those with novel coronavirus who have severely damaged lungs.

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COVID-19 Came to New York City From Europe, Not Asia

THURSDAY, April 9, 2020 (HealthDay News) -- The novel coronavirus has been circulating in New York City for longer than previously believed and most cases can be traced back to Europe, new research reveals.

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NIH Launches Clinical Trial of Hydroxychloroquine for COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A clinical trial to assess the antimalarial drug hydroxychloroquine as a treatment for adults with the novel coronavirus is now underway, the U.S. National Institutes of Health said Thursday.

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FDA Warns of False Claims That Chlorine Dioxide Can Treat COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A warning letter has been sent to a company marketing fraudulent and dangerous chlorine dioxide products for the prevention and treatment of the novel coronavirus, the U.S. Food and Drug Administration says.

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Another COVID-19 Vaccine Trial Begins in the United States

THURSDAY, April 9, 2020 (HealthDay News) -- Another clinical trial of an experimental vaccine for the novel coronavirus 2019 has been launched by U.S. researchers.

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Older Adults, Men, Preexisting Conditions Tied to COVID-19 Death

THURSDAY, April 9, 2020 (HealthDay News) -- Researchers have identified the most common clinical characteristics among 109 patients out of 1,017 with confirmed novel coronavirus pneumonia who died of COVID-19-related pneumonia in Wuhan, China; their findings were published online April 7 in the Annals of the American Thoracic Society.

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Convalescent Plasma Treatment Promising in Severe COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- One dose of convalescent plasma therapy is well tolerated and can potentially improve clinical symptoms in severe cases with coronavirus disease 2019, according to a study published online April 6 in the Proceedings of the National Academy of Sciences.

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ATS Provides Interim Guidance for Management of COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- In a guidance document issued by the American Thoracic Society, interim recommendations are presented for management of coronavirus disease 2019.

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HHS Report Looks at Hospital Experiences With COVID-19

THURSDAY, April 9, 2020 (HealthDay News) -- A report issued by the U.S. Department of Health and Human Services Office of Inspector General provides a national snapshot of hospital experiences in response to the coronavirus disease 2019.

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CDC Removes Prescribing Guidelines for Antimalarial Drugs

WEDNESDAY, April 8, 2020 (HealthDay News) -- Guidelines for doctors on how to prescribe two antimalarial drugs that some believe may treat the novel coronavirus are no longer available on the U.S. Centers for Disease Control and Prevention website.

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COVID-19 Killing Two Times More Men Than Women in NYC

WEDNESDAY, April 8, 2020 (HealthDay News) -- The novel coronavirus death rate in New York City is two times higher among men than among women, and men also have higher rates of infection and hospitalization, new data show.

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Children With COVID-19 Do Not Always Have Cough, Fever

WEDNESDAY, April 8, 2020 (HealthDay News) -- Children with coronavirus disease 2019 have symptoms of fever, cough, or shortness of breath less often than adults with the disease, according to research published in the April 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Surgical, Cotton Masks Not Effective for Filtering SARS-CoV-2

WEDNESDAY, April 8, 2020 (HealthDay News) -- For patients infected with severe acute respiratory syndrome coronavirus 2, neither surgical nor cotton masks effectively filter SARS-CoV-2 during coughs, according to a research letter published online April 6 in the Annals of Internal Medicine.

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Guidelines Developed for COVID-19 Patients in ICU

WEDNESDAY, April 8, 2020 (HealthDay News) -- In guidelines issued by the international Surviving Sepsis Campaign initiative, published in Critical Care Medicine and Intensive Care Medicine, recommendations are presented for the management of novel coronavirus disease 2019 patients in the intensive care unit.

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Children Have Milder Disease Course, Better COVID-19 Prognosis

WEDNESDAY, April 8, 2020 (HealthDay News) -- Children diagnosed with COVID-19 have a milder disease course and better prognoses than adults, according to a review published online March 23 in Acta Paediatrica.

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Side Effects Seen With Use of Chloroquine Against COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- The use of the antimalarial drug chloroquine to treat COVID-19 patients has been halted at several Swedish hospitals due to reported side effects such as cramps and loss of peripheral vision. Sahlgrenska University Hospital is one of those facilities. It stopped the use of chloroquine in the treatment of COVID-19 about two weeks ago.

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Serious Concerns Associated With COVID-19 Pandemic Reported

TUESDAY, April 7, 2020 (HealthDay News) -- Serious concerns are associated with coronavirus disease 2019, and many individuals are preparing by washing hands and self-isolating, according to a research letter published online April 7 in JAMA Internal Medicine.

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Compliance Higher if Stay-at-Home Extensions Are Shorter Than Thought

TUESDAY, April 7, 2020 (HealthDay News) -- When hypothetical stay-at-home orders in response to COVID-19 are extended longer than expected, people become less willing to increase self-isolation efforts, according to a working paper released by the National Bureau of Economic Research.

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Most COVID-19 Fatalities Are Men Over 50 With Chronic Disease

TUESDAY, April 7, 2020 (HealthDay News) -- Most fatal cases of coronavirus disease 2019 occur in men aged older than 50 years with noncommunicable chronic diseases, according to a study published online April 3 in the American Journal of Respiratory and Critical Care Medicine.

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Recommendations Issued for GI Procedures During COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- In a document issued by the American Gastroenterological Association, published online April 1 in Gastroenterology, recommendations are presented for gastrointestinal procedures during the coronavirus disease 2019 pandemic.

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School Closures Could Further Complicate COVID-19 Effort

TUESDAY, April 7, 2020 (HealthDay News) -- Potential contagion prevention from school closures needs to be weighed against the potential loss of health care workers due to child care obligations during the coronavirus disease 2019 pandemic, according to a study published online April 3 in The Lancet Public Health.

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No Treatment Change Needed for Peds IBD During COVID-19 Pandemic

TUESDAY, April 7, 2020 (HealthDay News) -- Preliminary data regarding outcomes for pediatric patients with inflammatory bowel disease during the coronavirus disease 2019 outbreak are reassuring, according to research published online March 31 in the Journal of Pediatric Gastroenterology and Nutrition.

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Radiotherapy for Prostate Cancer Adjusted During COVID-19

TUESDAY, April 7, 2020 (HealthDay News) -- In a special article published online April 1 in Advances in Radiation Oncology, a framework is laid out for the management of radiotherapy for prostate cancer patients during the coronavirus disease 2019 pandemic.

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FDA Authorizes Use of Chinese-Approved Masks in United States

MONDAY, April 6, 2020 (HealthDay News) -- Emergency use authorization of protective masks that do not meet American standards has been announced by the U.S. Food and Drug Administration.

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Majority of Physicians Report Serious Concerns About COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- According to a national survey conducted by Harvard Medical School, the RAND Corporation, and Doximity, practicing physicians currently report substantial concerns about supplies, the government response, and availability of testing amid the COVID-19 pandemic.

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Social Distancing Minimizes COVID-19 Spread in Assisted Living

MONDAY, April 6, 2020 (HealthDay News) -- Early implementation of social distancing and preventive measures after identification of coronavirus disease 2019 can minimize virus spread in senior independent and assisted living communities, according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Sentinel Surveillance Can Help Monitor Epidemiology of COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Rapid sentinel surveillance can help monitor the epidemiology of coronavirus disease 2019, according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Hydroxychloroquine Can Shorten Time to Recovery in COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Hydroxychloroquine can shorten time to clinical recovery and promote pneumonia absorption among patients with coronavirus disease 2019, according to a study that has not yet been peer reviewed and was posted online March 31 at medRxiv.org.

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Extracorporeal Membrane Oxygenation Might Aid in Severe COVID-19

MONDAY, April 6, 2020 (HealthDay News) -- Extracorporeal membrane oxygenation support might improve clinical outcomes in severe cases of coronavirus disease 2019 that cannot be adequately managed with mechanical ventilation alone, according to research published online March 30 in the ASAIO Journal.

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Comorbidity, Age, Time to Treatment Linked to COVID-19 Progression

MONDAY, April 6, 2020 (HealthDay News) -- Factors associated with coronavirus disease 2019 progression include comorbidity, age, and time from illness onset to antiviral treatment, according to a study published online March 27 in the Journal of Internal Medicine.

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Watch our latest HD Live! as we take a deep dive into the latest information on the COVID-19 vaccines, including the rollout process, potential side effects, supply and distribution.

Mabel Jong from our liveblog team speaks with Dr. Paul Offit, Director of the Vaccine Education Center and an attending physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia and one of the physicians on the FDA Vaccines and Related Biological Products Advisory Committee.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

HD Live! Videos

Our latest HD Live! discussion is on how healthcare in America could be impacted by a Trump or Biden victory.

Mabel Jong from our liveblog team speaks with Marianne Udow-Phillips, director of the Center for Health and Research Transformation at the University of Michigan, and Brian Blase, who served as a healthcare adviser to President Trump from 2017-2019 and is now president and CEO of Blase Policy Strategies.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is an overview of IDWeek, the annual meeting of leading infectious disease experts worldwide.

Mabel Jong from our liveblog team speaks with Dr. Inger Damon and Dr. Tom Talbot, IDWeek Chairs, for a summary of the latest data on a range of infectious diseases, including COVID-19.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is an overview of the American Academy of Pediatrics (AAP) national conference and exhibition.

Mabel Jong from our liveblog team speaks with AAP's Dr. Elizabeth Murray on the key takeaways of the event.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is on what could happen this flu season as COVID-19 still rages on across the country. How can we protect ourselves, and what can we and the health care system do to prepare for and potentially prevent a twindemic?

Mabel Jong from our liveblog team speaks with Dr. Nadia Eltaki, director of clinical operations at Sibley Memorial Hospital, on guidance on how to protect yourself and how a twindemic could impact the health care system.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is on loneliness and social isolation and how they can affect mental health. Plus, learn more about the survey we conducted with The Harris Poll on Americans and their use and knowledge of face masks and COVID-19.

Mabel Jong from our liveblog team speaks with Dr. Carla Perissinotto, a geriatrician and the associate chief for geriatrics clinical programs at UCSF, on advice on how to better care for seniors who might be more vulnerable to social isolation, and Kathy Steinberg, vice president of public release research at The Harris Poll, on the results of the HealthDay/The Harris Poll survey.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is on the upcoming COVID-19 vaccine and how the United States would need to prepare for a mass vaccination program.

Mabel Jong from our liveblog team speaks with Dr. Amesh Adalja from the Center for Health Security at Johns Hopkins University and Dr. Kelly Moore from Vanderbilt School of Medicine and associate director for immunization education with the Immunization Action Coalition.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! discussion is about getting college students back on campus safely and the COVID-19 testing measures that could help.

Mabel Jong from our liveblog team speaks with Professor David Paltiel, MBA, PhD from the Yale School of Public Health and Dr. Natasha Martin, an infectious disease modeler from UC San Diego leading the #ReturnToLearn program.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Each week, HealthDay's Physician's Briefing division rounds up the most important COVID-19 developments in the medical field. See this week's edition below for August 3-August 7.

U.S. Cancels Blanket Warning for International Travel

FRIDAY, Aug. 7, 2020 (HealthDay News) -- On Thursday, the Trump administration canceled its warnings against international travel because of the COVID-19 pandemic, the Associated Press reported.

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300,000 American Deaths Projected by December Without More Face Mask Use

FRIDAY, Aug. 7, 2020 (HealthDay News) -- As the U.S. COVID-19 case count neared 5 million on Thursday, a new model predicted that nearly 300,000 Americans could die of COVID-19 by December if more people do not wear masks or practice better social distancing.

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Telestroke Consultations Down During COVID-19 Pandemic

FRIDAY, Aug. 7, 2020 (HealthDay News) -- The median number of weekly consults seen through a telestroke network decreased during the COVID-19 pandemic, with Black patients significantly less likely to present with strokes, according to a study published online Aug. 5 in Stroke.

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SARS-CoV-2 Antibodies Detected in 13.7 Percent of NYC HCPs

FRIDAY, Aug. 7, 2020 (HealthDay News) -- Among health care providers in the New York City area, 13.7 percent have severe acute respiratory syndrome coronavirus 2 antibodies, a rate similar to adults randomly tested in New York state, according to a research letter published online Aug. 6 in the Journal of the American Medical Association.

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Moderna Charging Much More for COVID-19 Vaccine Than Others

FRIDAY, Aug. 7, 2020 (HealthDay News) -- Moderna is charging $37 a dose for its experimental vaccine, which is far more than what other companies say they plan to charge for their vaccines, CBS News reported Wednesday. Because two doses of the vaccine are needed to immunize people from COVID-19, total costs could be $74 per person.

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COVID-19 Tied to Higher Risk of Large Vessel Occlusion Strokes

FRIDAY, Aug. 7, 2020 (HealthDay News) -- COVID-19 is associated with large vessel occlusion strokes, according to a study published online July 29 in the American Journal of Roentgenology.

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Scientists Call for Broader Use of Faster COVID-19 Tests

THURSDAY, Aug. 6, 2020 (HealthDay News) -- As COVID-19 cases continue to surge across America, scientists on Wednesday called for widespread adoption of simpler, less accurate tests, as long as they are given often and quickly.

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Johnson & Johnson Makes $1 Billion Vaccine Deal

THURSDAY, Aug. 6, 2020 (HealthDay News) -- The U.S. government will pay Johnson & Johnson $1 billion for 100 million doses of its vaccine if it is approved by the U.S. Food and Drug Administration, the Washington Post reported Wednesday.

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Early Use of IL-6 Inhibitors May Improve COVID-19 Outcomes

THURSDAY, Aug. 6, 2020 (HealthDay News) -- For patients with severe COVID-19, administration of an interleukin-6 receptor inhibitor earlier in the disease course is associated with improved outcomes, according to a study published online July 25 in the International Journal of Infectious Diseases.

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ED Visits Decreased in Five States From January Through April 2020

THURSDAY, Aug. 6, 2020 (HealthDay News) -- As the COVID-19 pandemic intensified, there was a decrease in emergency department visits in five states from January through April 2020, according to a study published online Aug. 3 in JAMA Internal Medicine.

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Seven States Join Pact to Speed COVID-19 Testing

WEDNESDAY, Aug. 5, 2020 (HealthDay News) -- As the daily U.S. COVID-19 death toll averaged more than 1,000 for the ninth straight day on Tuesday, governors from seven states banded together to shorten turnaround time for COVID-19 test results.

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Experimental COVID-19 Vaccine Shows Encouraging Results

WEDNESDAY, Aug. 5, 2020 (HealthDay News) -- Maryland-based Novavax said Tuesday that preliminary trials of an experimental COVID-19 vaccine were promising.

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COVID-19 Case Fatality Rate 29 Percent in Multiple Myeloma Patients

WEDNESDAY, Aug. 5, 2020 (HealthDay News) -- For patients with multiple myeloma and COVID-19, the case fatality rate is 29 percent among hospitalized patients, with increased odds of adverse outcomes among racial/ethnic minorities, according to a study published online July 30 in Blood Cancer Discovery.

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Study Looks at Optimal Strategy for Reopening Schools in U.K.

WEDNESDAY, Aug. 5, 2020 (HealthDay News) -- Population-wide testing and effective contact tracing are necessary to prevent an epidemic rebound following school reopening in the United Kingdom; and severe acute respiratory syndrome coronavirus 2 transmission rates were low in an educational setting in Australia, according to two studies published online Aug. 3 in The Lancet Child & Adolescent Health.

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President Says Medicare Should Expand Telehealth Services

TUESDAY, Aug. 4, 2020 (HealthDay News) -- President Donald Trump signed an order on Monday that will broaden the role of telehealth for Medicare patients, the Associated Press reported.

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Trump's Plan Limits Free Nursing Home COVID-19 Tests

TUESDAY, Aug. 4, 2020 (HealthDay News) -- The plan to give every nursing home a fast COVID-19 testing machine has a catch, the Associated Press reported Tuesday. The catch is that under the Trump administration plan, the government will not give kits to check staff and residents more than a couple of times.

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Number of Newly ID'd U.S. Patients With Cancer Dropped During COVID-19

TUESDAY, Aug. 4, 2020 (HealthDay News) -- During the COVID-19 pandemic period, there was a significant decline in newly identified U.S. patients with six common types of cancer, according to a research letter published online Aug. 4 in JAMA Network Open.

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Burnout High Among Nonphysician Frontline Health Care Workers

TUESDAY, Aug. 4, 2020 (HealthDay News) -- More than 40 percent of nurses on the front lines during the pandemic may be experiencing burnout, according to a research letter published online Aug. 4 in JAMA Network Open.

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Risk for Positive COVID-19 Test Up for Health Care Workers

MONDAY, Aug. 3, 2020 (HealthDay News) -- Frontline health care workers have an increased risk for reporting a positive test for COVID-19, according to a study published online July 31 in The Lancet Public Health.

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Obesity Ups Risk for Intubation, Death With COVID-19 in Adults <65

MONDAY, Aug. 3, 2020 (HealthDay News) -- Obesity is associated with an increased risk for intubation or death among hospitalized adults with COVID-19, with the association observed in adults younger than 65 years but not in older adults, according to a study published online July 29 in the Annals of Internal Medicine.

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Risk for Acute Cerebrovascular Events Low in COVID-19 Patients

MONDAY, Aug. 3, 2020 (HealthDay News) -- For hospitalized COVID-19 patients, the risk for acute cerebrovascular events is low, according to a study published online July 20 in Stroke.

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