Back to top
Live:
Coronavirus Updates

Each week, HealthDay's Physician's Briefing division rounds up the most important COVID-19 developments in the medical field. See this week's edition below for April 20-April 24.

FDA Warns About Treating COVID-19 With Unproven Drugs

FRIDAY, April 24, 2020 (HealthDay News) -- Malaria drugs touted by some as potential "game changers" against COVID-19 are actually too dangerous for general use, the U.S. Food and Drug Administration warned Americans on Friday.

Read Full Article

Premature Posting of Remdesivir Findings Were 'Inconclusive'

FRIDAY, April 24, 2020 (HealthDay News) -- Inconclusive findings from a study investigating the antiviral drug remdesivir as a treatment for COVID-19 were posted to the World Health Organization website "prematurely," drug maker Gilead Sciences said Thursday.

Read Full Article

HTN, Obesity, Diabetes Common in U.S. COVID-19 Patients

FRIDAY, April 24, 2020 (HealthDay News) -- The most common comorbidities among patients hospitalized with COVID-19 in the New York City area are hypertension, obesity, and diabetes, according to a study published online April 22 in the Journal of the American Medical Association.

Read Full Article

Americans Report Concerns Over Their Mental Health During Pandemic

FRIDAY, April 24, 2020 (HealthDay News) -- Mental health concerns top economic worries during the COVID-19 pandemic, according to the results of a survey released by the University of Phoenix.

Read Full Article

COVID-19-Linked Changes Reported in Rheumatic Disease Patient Care

FRIDAY, April 24, 2020 (HealthDay News) -- Changes to health care have been reported among patients with rheumatic diseases during the COVID-19 pandemic, according to a study published online April 20 in ACR: Open Rheumatology.

Read Full Article

More Than One in Five Children in Home Confinement Report Depression

FRIDAY, April 24, 2020 (HealthDay News) -- During the COVID-19 outbreak in Hubei province in China, 22.6 percent of children in home confinement reported depressive symptoms, according to a research letter published online April 24 in JAMA Pediatrics.

Read Full Article

SARS-CoV-2 Stays in Respiratory Samples Longer in Severely Ill

FRIDAY, April 24, 2020 (HealthDay News) -- The median duration of severe acute respiratory syndrome coronavirus 2 RNA is significantly longer in the respiratory samples of patients with severe versus mild disease, according to a study published online April 21 in The BMJ.

Read Full Article

COVID-19 Outcomes Worse With Diabetes, Hyperglycemia

FRIDAY, April 24, 2020 (HealthDay News) -- Diabetes and/or uncontrolled hyperglycemia occur frequently among hospitalized patients with COVID-19 and are associated with worse outcomes, according to a study accepted for publication in the Journal of Diabetes Science and Technology.

Read Full Article

Survey Finds Anesthesiologists Prepared for COVID-19 Patients

FRIDAY, April 24, 2020 (HealthDay News) -- Anesthesiologists on the front lines of treating surgical COVID-19 patients in Turkey are generally knowledgeable about airway management, according to the results of a national survey published online April 6 in Surgical Infections.

Read Full Article

'Health Force' to Combat Pandemic Proposed by U.S. Senators

THURSDAY, April 23, 2020 (HealthDay News) -- A bill to create a "Health Force" to help combat the U.S. COVID-19 outbreak has been announced by two Democratic senators.

Read Full Article

White House Announces Payment Plan for Uninsured COVID-19 Patients

THURSDAY, April 23, 2020 (HealthDay News) -- A plan to begin paying hospitals and doctors who treat uninsured COVID-19 patients was announced by U.S. Health and Human Services Secretary Alex Azar on Wednesday.

Read Full Article

SARS-CoV-2 Can Spread Rapidly in Homeless Shelters

THURSDAY, April 23, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 can spread rapidly in homeless shelters, according to two studies published in the April 22 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

CDC: More Chemical Exposures Reported in January to March 2020

THURSDAY, April 23, 2020 (HealthDay News) -- In January to March 2020, there were more chemical exposures reported to the National Poison Data System than in the corresponding months of 2019 and 2018, according to research published in the April 20 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

ACEIs/ARBs Not Linked to Severity or Mortality of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- For patients with hypertension hospitalized with COVID-19 infections, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are not associated with the severity or mortality of COVID-19, according to a brief report published online April 23 in JAMA Cardiology.

Read Full Article

Mild, No Symptoms Seen for Most Children With SARS-CoV-2 Infection

THURSDAY, April 23, 2020 (HealthDay News) -- Most children with severe acute respiratory syndrome coronavirus 2 infection have mild respiratory symptoms or are asymptomatic, according to a review published online April 22 in JAMA Pediatrics.

Read Full Article

AAD Establishes Registry for Skin Manifestations of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- A registry has been created for reporting skin manifestations of COVID-19 following reports of patients presenting with skin conditions, including findings outlined in a letter to the editor published online March 26 in the Journal of the European Academy of Dermatology and Venereology.

Read Full Article

Lopinavir/Ritonavir, Umifenovir Ineffective for Mild COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- For patients hospitalized with mild/moderate COVID-19, lopinavir/ritonavir or umifenovir monotherapy offers little benefit, according to a study published online April 17 in Med.

Read Full Article

Rapid COVID-19 Test Can Produce False Negatives

WEDNESDAY, April 22, 2020 (HealthDay News) -- A widely used rapid COVID-19 test can produce false negatives if a certain solution is used to move or store patients' samples, the test's maker said.

Read Full Article

Expert Panel: There Are No Proven Drug Treatments for COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is no proven drug treatment for COVID-19 patients, according to a panel of experts convened by the U.S. National Institute of Allergy and Infectious Diseases.

Read Full Article

Hydroxychloroquine Seems Not to Cut Ventilator Use in COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is no evidence that use of hydroxychloroquine alone or with azithromycin reduces the risks for mechanical ventilation or death from any cause in patients hospitalized with COVID-19, according to a study that has not yet been peer reviewed and was posted online April 21 at medRxiv.org.

Read Full Article

ST-Segment Elevation Described in Patients With COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- For patients with COVID-19 who have ST-segment elevation, indicating potential acute myocardial infarction, there is considerable variability in presentation, and prognosis is poor, according to a letter to the editor published online April 17 in the New England Journal of Medicine.

Read Full Article

Obesity Ups Risk for COVID-19 Severity

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is a high frequency of obesity among patients admitted to intensive care for severe acute respiratory syndrome coronavirus 2, according to a study published online April 9 in Obesity.

Read Full Article

Scoring System Helps Guide Surgical Care During COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- A scoring system for medically necessary time-sensitive procedures can facilitate decision making and triage in the setting of COVID-19, according to a study published online April 9 in the Journal of the American College of Surgeons.

Read Full Article

LA County COVID-19 Infections Far Exceed Number of Confirmed Cases

TUESDAY, April 21, 2020 (HealthDay News) -- An early analysis of antibody testing from Los Angeles County reveals a COVID-19 infection rate that is up to 55 times the number of confirmed COVID-19 cases.

Read Full Article

FDA Authorizes COVID-19 Test That Uses Samples Collected at Home

TUESDAY, April 21, 2020 (HealthDay News) -- The U.S. Food and Drug Administration has approved emergency use of the first COVID-19 test that enables patients to take samples at home.

Read Full Article

Mental Health Consequences of COVID-19 Pandemic Explored

TUESDAY, April 21, 2020 (HealthDay News) -- A new position paper, published online April 15 in The Lancet Psychiatry, highlights the mental health consequences of COVID-19 management.

Read Full Article

COVID-19 Tied to Unique Nasal Symptoms

TUESDAY, April 21, 2020 (HealthDay News) -- COVID-19 is not associated with the symptoms typically associated with a viral cold or allergies, such as nasal blockage or mucus production, according to a review published online April 10 in Laryngoscope Investigative Otolaryngology.

Read Full Article

Expanding Symptom Screening Criteria Can Up COVID-19 Detection

TUESDAY, April 21, 2020 (HealthDay News) -- Expanding COVID-19 symptom screening criteria to include myalgias and chills could identify more health care personnel with the illness, according to a research letter published online April 17 in the Journal of the American Medical Association.

Read Full Article

176,190 U.S. Children Estimated to Have SARS-CoV-2 by April 6, 2020

TUESDAY, April 21, 2020 (HealthDay News) -- About 176,190 children nationwide were estimated to be infected with severe acute respiratory syndrome coronavirus 2 by April 6, 2020, according to a study published online April 16 in the Journal of Public Health Management & Practice.

Read Full Article

Coinfection With SARS-CoV-2, Other Respiratory Pathogens ID'd

TUESDAY, April 21, 2020 (HealthDay News) -- About 20 percent of specimens positive for severe acute respiratory syndrome coronavirus 2 infection are positive for other respiratory pathogens, according to a research letter published online April 15 in the Journal of the American Medical Association.

Read Full Article

Cardiac Cath Lab STEMI Activations Drop During Pandemic

TUESDAY, April 21, 2020 (HealthDay News) -- During the COVID-19 pandemic, there has been a 38 percent reduction in U.S. cardiac catheterization laboratory ST-segment elevation myocardial infarction activations, according to a research letter published online April 10 in the Journal of the American College of Cariology.

Read Full Article

Lab Protocol Failures Led to Ineffective COVID-19 Tests From CDC

MONDAY, April 20, 2020 (HealthDay News) -- The first COVID-19 tests in the United States were ineffective due to poor laboratory practices at the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration said.

Read Full Article

Public Health Measures Cut COVID-19 Transmission in Hong Kong

MONDAY, April 20, 2020 (HealthDay News) -- Public health measures implemented to suppress local transmission of COVID-19 in Hong Kong were associated with reduced transmission of COVID-19 and influenza, according to a study published online April 17 in The Lancet Public Health.

Read Full Article

Guidance Presented for Contact Lens Use During COVID-19

MONDAY, April 20, 2020 (HealthDay News) -- In an article published online April 3 in Contact Lens and Anterior Eye, important considerations are presented for contact lens wearers in the setting of the COVID-19 pandemic.

Read Full Article

COVID-19 Patients May Require ENT Consults for Varied Reasons

MONDAY, April 20, 2020 (HealthDay News) -- Patients with COVID-19 may require ear, nose, and throat consultations for many reasons, including tracheotomy, and protective strategies can prevent infection of otolaryngologists, according to a case series study accepted for publication in Otolaryngology-Head and Neck Surgery.

Read Full Article

Benefit of Social Distancing Outweighs Economic Impact

MONDAY, April 20, 2020 (HealthDay News) -- The economic benefits of lives saved through social distancing substantially outweigh the value of the projected losses to the U.S. economy, according to a study to be published in a forthcoming issue of the Journal of Benefit-Cost Analysis.

Read Full Article

Diabetes Increases Risk for Poorer Prognosis in COVID-19

MONDAY, April 20, 2020 (HealthDay News) -- Diabetes may contribute to more severe symptoms, rapid progression, and poorer prognosis in patients infected with COVID-19, according to a study published online March 31 in Diabetes Metabolism Research and Reviews.

Read Full Article

Each week, HealthDay's Physician's Briefing division rounds up the most important COVID-19 developments in the medical field. See this week's edition below for July 6-July 10.

Gilead Presents Additional Data on Efficacy of Remdesivir for COVID-19

FRIDAY, July 10, 2020 (HealthDay News) -- There is more good news on the effectiveness of the antiviral drug remdesivir against COVID-19, according to new clinical trial results from the drug's maker.

Read Full Article

Risk for COVID-19 Increased for Adults Taking PPIs

FRIDAY, July 10, 2020 (HealthDay News) -- Adults taking proton pump inhibitors have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship, according to a study published online July 7 in preprint format in the American Journal of Gastroenterology.

Read Full Article

WHO to Lead Investigation of COVID-19 Pandemic Origins

FRIDAY, July 10, 2020 (HealthDay News) -- The World Health Organization will lead an international investigation into the origins of the COVID-19 pandemic in China.

Read Full Article

Emphasizing Severity of COVID-19 Important for Teen Behaviors

FRIDAY, July 10, 2020 (HealthDay News) -- For adolescents, understanding the severity of COVID-19 and valuing social responsibility are associated with acting in socially responsible ways, including more social distancing and disinfecting, according to a study published online June 29 in JAMA Pediatrics.

Read Full Article

Children Seem Not to Be Driving SARS-COV-2 Transmission

FRIDAY, July 10, 2020 (HealthDay News) -- Children are mainly infected with severe acute respiratory syndrome coronavirus 2 in familial clusters, suggesting that transmission in schools is likely to be less than expected and that school closures are not necessary, according to a study and accompanying editorial published online July 10 in Pediatrics.

Read Full Article

COVID-19 Explored in Kidney Recipients, Hemodialysis Patients

FRIDAY, July 10, 2020 (HealthDay News) -- Many outpatient kidney transplant recipients with COVID-19 have symptomatic resolution without requiring hospitalization, and hospitalized COVID-19 patients on hemodialysis have worse outcomes than those without kidney failure, according to two studies recently published in the Clinical Journal of the American Society of Nephrology.

Read Full Article

Incidence of Takotsubo Cardiomyopathy Up During COVID-19

FRIDAY, July 10, 2020 (HealthDay News) -- The incidence of Takotsubo cardiomyopathy has increased during the COVID-19 pandemic, according to a study published online July 9 in JAMA Network Open.

Read Full Article

Sick Days Up for Some Essential Workers During COVID-19

THURSDAY, July 9, 2020 (HealthDay News) -- Increases in health-related workplace absenteeism were seen in April 2020 in personal care and service, health care support, and production occupations, according to research published in the July 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

COVID-19 Pandemic Exacerbates Mental Health Issues

THURSDAY, July 9, 2020 (HealthDay News) -- Just as the physical symptoms of COVID-19 vary among the population, mental health is enduring a variety of effects from the virus as well, according to Don Mordecai, M.D., national mental health and wellness lead at Kaiser Permanente, who recently spoke with HD Live! about the effects of the pandemic on mental health.

Read Full Article

Spectrum of Neurological Disorders Linked to SARS-CoV-2

THURSDAY, July 9, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 infection is associated with a spectrum of neurological disorders, according to a study published online July 8 in Brain.

Read Full Article

CDC Updates Info on COVID-19 Cases at Meat, Poultry Processing Facilities

THURSDAY, July 9, 2020 (HealthDay News) -- COVID-19 was confirmed in 16,233 workers in 239 meat and poultry processing facilities in 23 states through May 31, 2020, according to research published in the July 7 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Read Full Article

February to March 2020 Saw Surge in Hydroxychloroquine Rx

WEDNESDAY, July 8, 2020 (HealthDay News) -- From February to March 2020, there was a considerable increase in the number of patients receiving outpatient prescriptions for hydroxychloroquine, chloroquine, and azithromycin, according to a research letter published online July 6 in JAMA Internal Medicine.

Read Full Article

Multisystem Inflammatory Syndrome in Children Profiled

WEDNESDAY, July 8, 2020 (HealthDay News) -- Multisystem inflammatory syndrome in children, which coincided with COVID-19, is described in children and adolescents in the United States and New York state in two reports published online June 29 in the New England Journal of Medicine.

Read Full Article

Rising Number of People Report Anxiety, Depression During COVID-19

WEDNESDAY, July 8, 2020 (HealthDay News) -- New evidence shows that depression and anxiety are increasing as a result of the COVID-19 pandemic, according to the results of a survey released by Mental Health America.

Read Full Article

COVID-19 Antibody Cocktail Begins Late-Stage Human Trials

TUESDAY, July 7, 2020 (HealthDay News) -- Late-stage human trials to assess whether a double antibody cocktail can prevent and treat COVID-19 infection have started, biotechnology company Regeneron said Monday.

Read Full Article

Company Gets $1.6 Billion From U.S. Government for COVID-19 Vaccine

TUESDAY, July 7, 2020 (HealthDay News) -- Vaccine maker Novavax will receive $1.6 billion from the U.S. government to provide 100 million doses of a COVID-19 vaccine by early 2021, the Maryland-based company said Monday.

Read Full Article

Acute Ischemic Stroke Risk Higher With COVID-19 Than Influenza

TUESDAY, July 7, 2020 (HealthDay News) -- Patients with COVID-19 appear to have a heightened risk for acute ischemic stroke compared with patients with influenza, according to a study published online July 2 in JAMA Neurology.

Read Full Article

Social Distancing Effective for Mitigating COVID-19 Spread

TUESDAY, July 7, 2020 (HealthDay News) -- Social distancing is one of the main measures to combat COVID-19 spread, according to a study published online July 1 in The Lancet Infectious Diseases.

Read Full Article

Chilblains in Recent Case Series Not Tied to COVID-19 Infection

TUESDAY, July 7, 2020 (HealthDay News) -- In a case series of 31 patients, published online June 25 in JAMA Dermatology, chilblains did not appear to be directly associated with COVID-19.

Read Full Article

Major Medical Groups Urge Americans to Wear Face Masks

MONDAY, July 6, 2020 (HealthDay News) -- Three major medical groups are urging Americans to wear face masks, wash their hands, and practice social distancing as COVID-19 cases continue to surge in the United States.

Read Full Article

Fight Against COVID-19 Threatens Progress Against Other Diseases

MONDAY, July 6, 2020 (HealthDay News) -- Decades of progress against HIV, tuberculosis, malaria, and other diseases worldwide are threatened by the diversion of resources on the COVID-19 pandemic, the International AIDS Society says in a report to be published this week.

Read Full Article

FDA Warns About Hand Sanitizers With Methanol

MONDAY, July 6, 2020 (HealthDay News) -- A warning about hand sanitizer products that contain methanol (wood alcohol), a substance often used to create fuel and antifreeze, has been issued by the U.S. Food and Drug Administration.

Read Full Article

Scientists Say New Coronavirus Can Linger in Indoor Air

MONDAY, July 6, 2020 (HealthDay News) -- The new coronavirus can linger in indoor air and infect people, 239 scientists in 32 countries say in an open letter to the World Health Organization that challenges the WHO's position on how the virus is spread.

Read Full Article

Endotheliopathy ID'd in COVID-19, Tied to Higher Mortality Risk

MONDAY, July 6, 2020 (HealthDay News) -- Endotheliopathy is present in COVID-19 and is associated with critical illness and death, according to a study published online June 30 in The Lancet Haematology.

Read Full Article

Outcomes Similar for COVID-19 in Patients With, Without HIV

MONDAY, July 6, 2020 (HealthDay News) -- Persons with HIV hospitalized with COVID-19 have similar outcomes to demographically matched patients without HIV, according to a study published online June 28 in Clinical Infectious Diseases.

Read Full Article

Most Using Online COVID-19 Tool Report Mild, Moderate Symptoms

MONDAY, July 6, 2020 (HealthDay News) -- The majority of individuals using an online COVID-19 self-assessment tool report mild or moderate symptoms possibly associated with COVID-19, according to research published online June 15 in the Journal of General Internal Medicine.

Read Full Article

HD Live! Videos

Our latest HD Live! discussion is on how countries have contained COVID-19 and whether the United States can do the same with universal masking and certain other health strategies.

Mabel Jong from our liveblog team speaks with Dr. Robert Brook, a professor of medicine at UCLA and the distinguished chair in the health care services program at the RAND Corporation, and Dr. May Chu, a clinical professor of epidemiology with the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus.

Watch our in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

They contend that much smaller exhaled droplets can travel the length of a room and cause infection when inhaled.

Scientists Say New Coronavirus Can Linger in Indoor Air

MONDAY, July 6, 2020 (HealthDay News) -- The new coronavirus can linger in indoor air and infect people, 239 scientists in 32 countries say in an open letter to the World Health Organization that challenges the WHO's position on how the virus is spread.

The WHO says the virus is spread primarily by large respiratory droplets expelled by infected people in coughs and sneezes but that those droplets fall quickly to the floor instead of remaining in the air, The New York Times reported. But the scientists' letter contends that much smaller exhaled droplets can travel the length of a room through the air and cause infection when they are inhaled. They plan to publish their letter next week in a scientific journal.

If this type of airborne transmission plays a significant role in the pandemic, there are major implications, according to The Times. Masks may be required indoors, building ventilation systems may need to minimize recirculating air, ultraviolet lights may be required to kill airborne viral particles, and health care workers may need masks that filter out even the smallest respiratory droplets as they care for COVID-19 patients.

Read the full HealthDay story.

Methanol can be toxic when absorbed through the skin and life-threatening when ingested.

FDA Warns About Hand Sanitizers With Methanol

MONDAY, July 6, 2020 (HealthDay News) -- A warning about hand sanitizer products that contain methanol (wood alcohol), a substance often used to create fuel and antifreeze, has been issued by the U.S. Food and Drug Administration.

Methanol can be toxic when absorbed through the skin and life-threatening when ingested, and it is not an acceptable active ingredient for hand sanitizer products, according to the FDA. The agency said it has seen an increase in hand sanitizer products that are labeled to contain ethanol (also known as ethyl alcohol) but that have tested positive for methanol. Methanol exposure can result in nausea, vomiting, headache, blurred vision, permanent blindness, seizures, coma, permanent damage to the nervous system, or death.

State officials have reported recent harm among adults and children who ingested hand sanitizer products contaminated with methanol, including blindness, hospitalization, and death, the FDA said. Consumers who have hand sanitizers with methanol should immediately stop using them and dispose of the bottle in a hazardous waste container, if available, or dispose of it as recommended by their local waste management and recycling center. There is a list of FDA-tested and recalled hand sanitizers on the agency's website.

Read the full HealthDay story.

In many cities, a combination of factors are fueling the problem: a shortage of key supplies, backlogs at laboratories that perform the tests, and surging infection counts as cases climb in almost 40 states.

U.S. Coronavirus Cases Near 3 Million as Hospitals in Sun Belt Fill Up With Patients

TUESDAY, July 7, 2020 (HealthDay News) -- With the number of coronavirus cases in the United States approaching 3 million on Monday, hospitals across the Sun Belt continued to be flooded with COVID-19 patients.

Arizona reached 89 percent capacity for ICU beds, as Alabama, California, Georgia, North Carolina, South Carolina and Texas also reported unprecedented numbers of hospitalizations, the Washington Post reported.

For the 28th day in a row, the country's rolling seven-day average of daily new cases obliterated previous records, though the number of deaths nationwide has remained relatively stable, the newspaper reported.

Read the full HealthDay story.

Authors say self-assessment tool could ease burden on health care system and collect useful information.

Most Using Online COVID-19 Tool Report Mild, Moderate Symptoms

MONDAY, July 6, 2020 (HealthDay News) -- The majority of individuals using an online COVID-19 self-assessment tool report mild or moderate symptoms possibly associated with COVID-19, according to research published online June 15 in the Journal of General Internal Medicine.

William M. Mehring, from the Keck School of Medicine at the University of Southern California in Los Angeles, and colleagues developed a web-based COVID-19 self-assessment tool, available in English and Spanish, and report the results of 276,560 digital self-assessments.

The researchers report that of the 5,611 users who entered optional demographic data, 61 percent were female (mean age, 39 years). In more than two-thirds of self-assessments (69.6 percent), users reported symptoms potentially attributable to COVID-19. Among the reported symptoms potentially attributable to COVID-19, the majority (80.5 percent) reported mild or moderate symptoms that could likely be managed with home self-care, while 19.5 percent reported severe symptoms for which the tool recommended immediate medical attention. Of individuals reporting mild symptoms, 7.1 percent said they had direct exposure to someone with confirmed COVID-19.

Read the full HealthDay story.

Soluble thrombomodulin concentration >3.26 ng/mL linked to lower rates of hospital discharge and survival.

Endotheliopathy ID'd in COVID-19, Tied to Higher Mortality Risk

MONDAY, July 6, 2020 (HealthDay News) -- Endotheliopathy is present in COVID-19 and is associated with critical illness and death, according to a study published online June 30 in The Lancet Haematology.

George Goshua, M.D., from the Yale School of Medicine in New Haven, Connecticut, and colleagues conducted a single-center study involving hospitalized adult patients with laboratory-confirmed COVID-19 from the medical intensive care unit (ICU) or a specialized non-ICU COVID-19 floor (48 and 20 patients, respectively); 13 asymptomatic nonhospitalized controls were recruited as a comparator group. Markers of endothelial cell and platelet activations were assessed and the levels were compared for ICU patients, non-ICU patients, and controls.

The researchers found that compared with non-ICU patients, in ICU patients, markers of endothelial cell and platelet activation were significantly elevated, including von Willebrand Factor (VWF) antigen (mean, 565 percent in ICU patients versus 278 percent in non-ICU patients) and soluble P-selectin (15.9 versus 11.2 ng/mL). In 16 of 20 non-ICU patients, VWF antigen concentrations were also elevated above the normal range. Among all patients, there was a significant association between mortality and VWF antigen and soluble thrombomodulin. Soluble thrombomodulin concentrations greater than 3.26 ng/mL were associated with lower rates of hospital discharge (88 versus 52 percent) and a lower likelihood of survival (hazard ratio, 5.9).

Read the full HealthDay story.

See what experts have to say about the toll of the COVID-19 pandemic on mental health.

Will the COVID-19 Pandemic Leave a Mental Health Crisis in Its Wake?

MONDAY, July 6, 2020 (HealthDay News) -- Stressed from home-schooling your kids? Lonely from lockdown? Worried about a sick loved one isolated in a nursing home? Worried you might lose your job?

The ongoing COVID-19 pandemic is affecting everyone's mental health in ways small and large, and experts are concerned that for many, today's anxiety will become a tidal wave of mental health problems in the years ahead.

The pandemic is adding to what already was an underrecognized mental health crisis in the United States, according to Dr. Don Mordecai, national mental health and wellness lead at Kaiser Permanente in Oakland, Calif.

Read the full HealthDay story.

In a small study, all 10 patients who had severe COVID-19 symptoms produced T-cells that worked with antibodies to try to kill the virus and stop the infection.

How Immune System Fights COVID-19 May Be Key to Vaccine Success

MONDAY, July 6, 2020 (HealthDay News) -- Even the sickest COVID-19 patients make T-cells to fight the infection, a new study finds.

This means that a COVID-19 vaccine will have to cause the body to make T-cells along with antibodies, researchers say.

The immune response to the SARS-CoV-2 virus, which causes COVID-19, was the same in American and Dutch patients in the study.

Read the full HealthDay story.