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Researchers reported that blocking testosterone may help prevent COVID-19 in men, based on research that Italian men with prostate cancer on androgen-deprivation therapy (ADT) were less likely to get infected with COVID-19 and had less severe cases if they were infected. An enzyme COVID-19 needs to infect cells was blocked by ADT.

Could Lower Testosterone Help Men Ward Off COVID-19?

THURSDAY, May 7, 2020 (HealthDay News) -- Many drugs are being tested to fight COVID-19, but now researchers report that blocking testosterone might help prevent the infection in men.

Italian men with prostate cancer on androgen-deprivation therapy (ADT) were less likely to get infected with COVID-19 and had less severe cases if they were infected, the researchers found.

Lead researcher Dr. Andrea Alimonti, an oncologist at the Università della Svizzera Italiana in Bellinzona, Switzerland, thinks it might be worth trying this therapy on men with severe cases of COVID-19.

"This could give us a therapeutic window to treat patients that have been infected and haven't gotten better, to see whether this therapy would lead them to recover faster or to decrease the severity of their symptoms," he said.

Alimonti's interest was piqued when he saw data that men were more likely to develop COVID-19 than women and suffer more severe bouts of the disease.

Putting two and two together, he realized that an enzyme (TMPRSS2), which COVID-19 needs to infect cells, was blocked by androgen-deprivation therapy.

Read the full HealthDay story.

Watch our latest HealthDay Now as we recap the highlights of the American Association for Cancer Research (AACR) Annual Meeting 2021.

Mabel Jong from our liveblog team speaks with Dr. Antoni Ribas, former president of the American Association for Cancer Research and professor of medicine at UCLA, and Anna Plym, PhD, a postdoctoral research fellow at Brigham and Women's Hospital.

Watch the in-depth discussion above, and see our past HealthDay Nows and other videos on our YouTube channel.

HD Live! Videos

Watch our latest HD Live! as we take a look at the COVID-19 pandemic and the vaccination rollout and how they've impacted people of color.

Mabel Jong from our liveblog team speaks with:

  • Tasha Clark-Amar, CEO, East Baton Rouge Council on Aging
  • Jill Ramirez, Executive Director, Latino HealthCare Forum (Austin)
  • Vickie Mays, PhD, Professor, UCLA Fielding School of Public Health

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a look at the global COVID-19 vaccination rollout and how the United States rollout compares.

Mabel Jong from our liveblog team speaks with Dr. Ran Balicer of Clalit Health Services and Dr. Arnold Monto of University of Michigan School of Public Health.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

UPDATE 1/26/21: Since our HD Live! interview with CEO Andrei Doroshin, the Philadelphia Health Department has severed its ties with the organization. The nonprofit has changed its status to a for-profit entity.

Watch our latest HD Live! as we take a look at Philly Fighting Covid, a nonprofit organization run by graduate students from Drexel University that aims to help with mass COVID-19 vaccination in Philadelphia.

Mabel Jong from our liveblog team speaks with Andrei Doroshin, founder of Philly Fighting Covid.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a deep dive into the vaccine rollout across the country.

Mabel Jong from our liveblog team speaks with Dr. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota and a member of the Biden COVID-19 Advisory Board.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a deep dive into the latest information on the COVID-19 vaccines, including the rollout process, potential side effects, supply and distribution.

Mabel Jong from our liveblog team speaks with Dr. Paul Offit, Director of the Vaccine Education Center and an attending physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia and one of the physicians on the FDA Vaccines and Related Biological Products Advisory Committee.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! as we take a look back and a look ahead at COVID-19 and its impact on the United States and its healthcare workers.

Mabel Jong from our liveblog team speaks with Dr. David Shulkin, former Secretary of Veterans Affairs, ex-CEO of Beth Israel Medical Center in New York and an accomplished healthcare executive, and Dr. Joel Zivot, anesthesiologist and clinician at Emory University Hospital ICU.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Watch our latest HD Live! with Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID).

Mabel Jong from our liveblog team speaks with Dr. Anthony Fauci about the latest on COVID-19, including the vaccines, the infection rates and the future.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.

Our latest HD Live! is a conference wrap-up of the American Heart Association Scientific Sessions 2020.

Mabel Jong from our liveblog team speaks with Dr. Donald Lloyd-Jones, American Heart Association President-Elect, for a summary of the highlights of the AHA Scientific Sessions 2020.

Watch the in-depth discussion above, and see our past HD Lives and other videos on our YouTube channel.